Gene Could Link Autism to Digestive Problems

By Liz Szabo, USA TODAY

Researchers are studying a gene that may cause both autism and gastrointestinal disorders, a study in Monday’s Pediatrics reports.

More than 30% of people with autism also have some kind of stomach or intestinal problem, compared with fewer than 10% of people who aren’t autistic, says study author Daniel Campbell, research assistant professor at Vanderbilt University.

Campbell is focusing on a gene called MET, which is involved in brain development before birth and in connections between brain cells after birth, as well as in the process through which the gastrointestinal system repairs itself. In his study, a variation in this gene was associated with both autism and gastrointestinal problems in 118 of 214 families. But researchers found no link to the genetic variation in autistic patients who didn’t have gastrointestinal problems.

That suggests the genetic variation may be responsible for causing autism in this specific group of people, although it may not be related to other cases of autism, Campbell says.

As scientists learn more about the disease, Campbell says, it appears that autism is not a single disease but a spectrum of disorders with common symptoms but different causes.

Campbell’s research was financed by the National Institutes of Health, a private group called Cure Autism Now and other sources.

Some researchers say Campbell’s findings, although intriguing, are preliminary.

Hakon Hakonarson, an autism researcher and director of Children’s Hospital of Philadelphia’s Center for Applied Genomics, says it would be surprising for one gene to be responsible for the wide variety of problems included in the study: chronic constipation, chronic diarrhea, reflux, irritable bowel syndrome and ulcers.

Researchers need to try to replicate their findings in a different group of people to prove that the results were not just the result of chance, says Hakonarson, who was not involved in the study.

Campbell says he’s working on a more definitive study. In his current paper, he relied on parents to describe their children’s gastrointestinal difficulties. In his new project, children will be seen by a gastroenterologist, who will be able to confirm the gastrointestinal problems.

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  235. Superb blog! Do you have any recommendations for aspiring writers? I’m planning to start my own site soon but I’m a little lost on everything. Would you recommend starting with a free platform like WordPress or go for a paid option? There are so many options out there that I’m completely overwhelmed .. Any recommendations? Kudos!

  236. Hey there, I think your website might be having browser compatibility issues. When I look at your blog site in Ie, it looks fine but when opening in Internet Explorer, it has some overlapping. I just wanted to give you a quick heads up! Other then that, awesome blog!

  237. My coder is trying to convince me to move to .net from PHP. I have always disliked the idea because of the expenses. But he’s tryiong none the less. I’ve been using Movable-type on various websites for about a year and am concerned about switching to another platform. I have heard excellent things about blogengine.net. Is there a way I can import all my wordpress content into it? Any kind of help would be greatly appreciated!

  238. I do not know whether it’s just me or if perhaps everyone else experiencing problems with your blog. It looks like some of the text on your posts are running off the screen. Can someone else please comment and let me know if this is happening to them too? This may be a issue with my internet browser because I’ve had this happen previously. Many thanks

  239. Hi! Someone in my Myspace group shared this website with us so I came to take a look. I’m definitely enjoying the information. I’m bookmarking and will be tweeting this to my followers! Wonderful blog and superb design.

  240. Hi there! I realize this is somewhat off-topic however I had to ask. Does operating a well-established blog such as yours require a lot of work? I am brand new to blogging but I do write in my journal everyday. I’d like to start a blog so I can easily share my experience and views online. Please let me know if you have any suggestions or tips for new aspiring bloggers. Thankyou!

  241. I’m not sure exactly why but this blog is loading extremely slow for me. Is anyone else having this problem or is it a problem on my end? I’ll check back later and see if the problem still exists.

  242. Write more, thats all I have to say. Literally, it seems as though you relied on the video to make your point. You definitely know what youre talking about, why throw away your intelligence on just posting videos to your blog when you could be giving us something enlightening to read?

  243. Howdy! I realize this is sort of off-topic however I had to ask. Does running a well-established website like yours require a massive amount work? I am completely new to writing a blog however I do write in my journal on a daily basis. I’d like to start a blog so I can share my experience and views online. Please let me know if you have any kind of suggestions or tips for brand new aspiring bloggers. Thankyou!

  244. I am curious to find out what blog platform you’re working with? I’m experiencing some minor security problems with my latest website and I’d like to find something more safe. Do you have any solutions?

  245. Today, I went to the beach front with my children. I found a sea shell and gave it to my 4 year old daughter and said “You can hear the ocean if you put this to your ear.” She placed the shell to her ear and screamed. There was a hermit crab inside and it pinched her ear. She never wants to go back! LoL I know this is entirely off topic but I had to tell someone!

  246. Please let me know if you’re looking for a article writer for your blog. You have some really great posts and I think I would be a good asset. If you ever want to take some of the load off, I’d love to write some articles for your blog in exchange for a link back to mine. Please shoot me an e-mail if interested. Thank you!

  247. Hello there! I know this is somewhat off topic but I was wondering if you knew where I could get a captcha plugin for my comment form? I’m using the same blog platform as yours and I’m having difficulty finding one? Thanks a lot!

  248. I know this if off topic but I’m looking into starting my own weblog and was wondering what all is needed to get setup? I’m assuming having a blog like yours would cost a pretty penny? I’m not very internet savvy so I’m not 100% positive. Any suggestions or advice would be greatly appreciated. Appreciate it

  249. Whats up are using WordPress for your site platform? I’m new to the blog world but I’m trying to get started and create my own. Do you need any coding knowledge to make your own blog? Any help would be really appreciated!

  250. Hi just wanted to give you a brief heads up and let you know a few of the images aren’t loading correctly. I’m not sure why but I think its a linking issue. I’ve tried it in two different web browsers and both show the same outcome.

  251. Hey there! This post could not be written any better! Reading this post reminds me of my good old room mate! He always kept chatting about this. I will forward this write-up to him. Fairly certain he will have a good read. Many thanks for sharing!

  252. I am really enjoying the theme/design of your site. Do you ever run into any internet browser compatibility problems? A number of my blog readers have complained about my website not operating correctly in Explorer but looks great in Opera. Do you have any recommendations to help fix this issue?

  253. Hello! Quick question that’s totally off topic. Do you know how to make your site mobile friendly? My website looks weird when browsing from my apple iphone. I’m trying to find a theme or plugin that might be able to resolve this issue. If you have any recommendations, please share. Appreciate it!

  254. I love your blog.. very nice colors & theme. Did you create this website yourself or did you hire someone to do it for you? Plz reply as I’m looking to design my own blog and would like to know where u got this from. kudos

  255. My developer is trying to persuade me to move to .net from PHP. I have always disliked the idea because of the expenses. But he’s tryiong none the less. I’ve been using WordPress on various websites for about a year and am worried about switching to another platform. I have heard great things about blogengine.net. Is there a way I can import all my wordpress posts into it? Any kind of help would be greatly appreciated!

  256. Hola! I’ve been reading your web site for a long time now and finally got the bravery to go ahead and give you a shout out from Huffman Tx! Just wanted to tell you keep up the great work!

  257. Howdy just wanted to give you a quick heads up. The words in your content seem to be running off the screen in Safari. I’m not sure if this is a formatting issue or something to do with browser compatibility but I figured I’d post to let you know. The layout look great though! Hope you get the problem solved soon. Many thanks

  258. Greetings from Ohio! I’m bored to death at work so I decided to browse your site on my iphone during lunch break. I love the information you provide here and can’t wait to take a look when I get home. I’m shocked at how quick your blog loaded on my cell phone .. I’m not even using WIFI, just 3G .. Anyhow, awesome blog!

  259. Hmm it looks like your site ate my first comment (it was super long) so I guess I’ll just sum it up what I submitted and say, I’m thoroughly enjoying your blog. I too am an aspiring blog blogger but I’m still new to everything. Do you have any helpful hints for beginner blog writers? I’d definitely appreciate it.

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  261. Howdy! I know this is kinda off topic nevertheless I’d figured I’d ask. Would you be interested in trading links or maybe guest writing a blog article or vice-versa? My website addresses a lot of the same topics as yours and I believe we could greatly benefit from each other. If you’re interested feel free to send me an e-mail. I look forward to hearing from you! Fantastic blog by the way!

  262. Hello, i read your blog from time to time and i own a similar one and i was just wondering if you get a lot of spam comments? If so how do you reduce it, any plugin or anything you can recommend? I get so much lately it’s driving me mad so any support is very much appreciated.

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  264. Write more, thats all I have to say. Literally, it seems as though you relied on the video to make your point. You definitely know what youre talking about, why throw away your intelligence on just posting videos to your blog when you could be giving us something enlightening to read?

  265. Hmm is anyone else encountering problems with the pictures on this blog loading? I’m trying to determine if its a problem on my end or if it’s the blog. Any feedback would be greatly appreciated.

  266. Great blog! Do you have any hints for aspiring writers? I’m planning to start my own site soon but I’m a little lost on everything. Would you recommend starting with a free platform like WordPress or go for a paid option? There are so many options out there that I’m totally overwhelmed .. Any suggestions? Thank you!

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  268. Hey! I know this is kinda off topic but I was wondering which blog platform are you using for this site? I’m getting sick and tired of WordPress because I’ve had issues with hackers and I’m looking at alternatives for another platform. I would be great if you could point me in the direction of a good platform.

  269. Greetings from Idaho! I’m bored to death at work so I decided to browse your blog on my iphone during lunch break. I enjoy the information you provide here and can’t wait to take a look when I get home. I’m shocked at how fast your blog loaded on my cell phone .. I’m not even using WIFI, just 3G .. Anyhow, superb site!

  270. Hello! This is my first comment here so I just wanted to give a quick shout out and say I really enjoy reading through your articles. Can you recommend any other blogs/websites/forums that go over the same topics? Thanks a lot!

  271. Have you ever thought about adding a little bit more than just your articles? I mean, what you say is important and everything. However imagine if you added some great graphics or videos to give your posts more, “pop”! Your content is excellent but with pics and video clips, this website could definitely be one of the very best in its niche. Great blog!

  272. Hello, i read your blog from time to time and i own a similar one and i was just wondering if you get a lot of spam comments? If so how do you protect against it, any plugin or anything you can suggest? I get so much lately it’s driving me crazy so any assistance is very much appreciated.

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  278. The other day, while I was at work, my cousin stole my iphone and tested to see if it can survive a twenty five foot drop, just so she can be a youtube sensation. My iPad is now broken and she has 83 views. I know this is totally off topic but I had to share it with someone!

  279. Have you ever considered publishing an ebook or guest authoring on other sites? I have a blog based upon on the same ideas you discuss and would really like to have you share some stories/information. I know my visitors would value your work. If you are even remotely interested, feel free to send me an e mail.

  280. I am really loving the theme/design of your blog. Do you ever run into any web browser compatibility issues? A few of my blog audience have complained about my blog not working correctly in Explorer but looks great in Opera. Do you have any recommendations to help fix this problem?

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  284. Please let me know if you’re looking for a article author for your weblog. You have some really good posts and I think I would be a good asset. If you ever want to take some of the load off, I’d absolutely love to write some articles for your blog in exchange for a link back to mine. Please blast me an e-mail if interested. Many thanks!

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  286. Write more, thats all I have to say. Literally, it seems as though you relied on the video to make your point. You definitely know what youre talking about, why throw away your intelligence on just posting videos to your blog when you could be giving us something enlightening to read?

  287. Do you mind if I quote a few of your articles as long as I provide credit and sources back to your website? My website is in the very same area of interest as yours and my visitors would really benefit from some of the information you provide here. Please let me know if this ok with you. Many thanks!

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  289. Hi there! I know this is somewhat off topic but I was wondering which blog platform are you using for this website? I’m getting fed up of WordPress because I’ve had problems with hackers and I’m looking at options for another platform. I would be awesome if you could point me in the direction of a good platform.

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  291. Greetings from Carolina! I’m bored to tears at work so I decided to browse your blog on my iphone during lunch break. I love the information you present here and can’t wait to take a look when I get home. I’m amazed at how quick your blog loaded on my phone .. I’m not even using WIFI, just 3G .. Anyhow, good site!

  292. Hey there! I’ve been following your blog for some time now and finally got the bravery to go ahead and give you a shout out from New Caney Texas! Just wanted to tell you keep up the good job!

  293. Hello, I think your blog might be having browser compatibility issues. When I look at your blog site in Firefox, it looks fine but when opening in Internet Explorer, it has some overlapping. I just wanted to give you a quick heads up! Other then that, amazing blog!

  294. Greetings from Los angeles! I’m bored at work so I decided to browse your site on my iphone during lunch break. I enjoy the knowledge you provide here and can’t wait to take a look when I get home. I’m shocked at how quick your blog loaded on my mobile .. I’m not even using WIFI, just 3G .. Anyhow, good blog!

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  296. Greetings from Los angeles! I’m bored to tears at work so I decided to browse your blog on my iphone during lunch break. I really like the knowledge you provide here and can’t wait to take a look when I get home. I’m shocked at how quick your blog loaded on my mobile .. I’m not even using WIFI, just 3G .. Anyhow, awesome site!

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  298. Do you have a spam problem on this blog; I also am a blogger, and I was curious about your situation; we have created some nice procedures and we are looking to trade strategies with other folks, be sure to shoot me an email if interested.

  299. Hmm is anyone else experiencing problems with the pictures on this blog loading? I’m trying to figure out if its a problem on my end or if it’s the blog. Any feed-back would be greatly appreciated.

  300. This design is spectacular! You most certainly know how to keep a reader entertained. Between your wit and your videos, I was almost moved to start my own blog (well, almost…HaHa!) Great job. I really enjoyed what you had to say, and more than that, how you presented it. Too cool!

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  302. I’m not sure exactly why but this blog is loading incredibly slow for me. Is anyone else having this problem or is it a problem on my end? I’ll check back later and see if the problem still exists.

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  304. I really like your blog.. very nice colors & theme. Did you create this website yourself or did you hire someone to do it for you? Plz answer back as I’m looking to construct my own blog and would like to know where u got this from. kudos

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  307. Heya just wanted to give you a quick heads up and let you know a few of the pictures aren’t loading properly. I’m not sure why but I think its a linking issue. I’ve tried it in two different web browsers and both show the same results.

  308. Hey I know this is off topic but I was wondering if you knew of any widgets I could add to my blog that automatically tweet my newest twitter updates. I’ve been looking for a plug-in like this for quite some time and was hoping maybe you would have some experience with something like this. Please let me know if you run into anything. I truly enjoy reading your blog and I look forward to your new updates.

  309. Heya just wanted to give you a brief heads up and let you know a few of the pictures aren’t loading properly. I’m not sure why but I think its a linking issue. I’ve tried it in two different internet browsers and both show the same outcome.

  310. Hi there! This is my 1st comment here so I just wanted to give a quick shout out and tell you I truly enjoy reading through your blog posts. Can you suggest any other blogs/websites/forums that go over the same subjects? Thanks!

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  312. Hey there, I think your site might be having browser compatibility issues. When I look at your blog in Ie, it looks fine but when opening in Internet Explorer, it has some overlapping. I just wanted to give you a quick heads up! Other then that, amazing blog!

  313. I’m really loving the theme/design of your blog. Do you ever run into any browser compatibility problems? A number of my blog audience have complained about my site not working correctly in Explorer but looks great in Firefox. Do you have any solutions to help fix this problem?

  314. Does your site have a contact page? I’m having a tough time locating it but, I’d like to shoot you an e-mail. I’ve got some recommendations for your blog you might be interested in hearing. Either way, great site and I look forward to seeing it improve over time.

  315. Write more, thats all I have to say. Literally, it seems as though you relied on the video to make your point. You definitely know what youre talking about, why throw away your intelligence on just posting videos to your blog when you could be giving us something enlightening to read?

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  318. Hi there would you mind stating which blog platform you’re working with? I’m going to start my own blog soon but I’m having a hard time choosing between BlogEngine/Wordpress/B2evolution and Drupal. The reason I ask is because your design seems different then most blogs and I’m looking for something unique. P.S Apologies for being off-topic but I had to ask!

  319. Howdy are using WordPress for your blog platform? I’m new to the blog world but I’m trying to get started and set up my own. Do you require any coding knowledge to make your own blog? Any help would be greatly appreciated!

  320. Hello, i read your blog occasionally and i own a similar one and i was just curious if you get a lot of spam responses? If so how do you protect against it, any plugin or anything you can suggest? I get so much lately it’s driving me crazy so any help is very much appreciated.

  321. I was suggested this web site by my cousin. I’m not sure whether this post is written by him as no one else know such detailed about my trouble. You are amazing! Thanks!

  322. Do you have a spam issue on this site; I also am a blogger, and I was curious about your situation; we have created some nice practices and we are looking to exchange strategies with others, be sure to shoot me an e-mail if interested.

  323. Do you mind if I quote a few of your articles as long as I provide credit and sources back to your blog? My website is in the exact same area of interest as yours and my users would definitely benefit from a lot of the information you present here. Please let me know if this ok with you. Thanks!

  324. Hey! Do you know if they make any plugins to help with Search Engine Optimization? I’m trying to get my blog to rank for some targeted keywords but I’m not seeing very good gains. If you know of any please share. Many thanks!

  325. Great blog! Do you have any tips and hints for aspiring writers? I’m hoping to start my own site soon but I’m a little lost on everything. Would you suggest starting with a free platform like WordPress or go for a paid option? There are so many choices out there that I’m completely overwhelmed .. Any tips? Thank you!

  326. Have you ever thought about creating an ebook or guest authoring on other websites? I have a blog based on the same subjects you discuss and would really like to have you share some stories/information. I know my audience would value your work. If you are even remotely interested, feel free to send me an e mail.

  327. I know this if off topic but I’m looking into starting my own weblog and was curious what all is needed to get setup? I’m assuming having a blog like yours would cost a pretty penny? I’m not very internet savvy so I’m not 100% sure. Any recommendations or advice would be greatly appreciated. Appreciate it

  328. I’m really loving the theme/design of your web site. Do you ever run into any web browser compatibility problems? A couple of my blog visitors have complained about my blog not operating correctly in Explorer but looks great in Firefox. Do you have any tips to help fix this issue?

  329. Hmm it looks like your site ate my first comment (it was super long) so I guess I’ll just sum it up what I had written and say, I’m thoroughly enjoying your blog. I too am an aspiring blog blogger but I’m still new to the whole thing. Do you have any tips and hints for newbie blog writers? I’d genuinely appreciate it.

  330. Heya! I understand this is somewhat off-topic however I had to ask. Does building a well-established website like yours take a lot of work? I’m completely new to writing a blog but I do write in my diary daily. I’d like to start a blog so I can easily share my own experience and thoughts online. Please let me know if you have any kind of recommendations or tips for brand new aspiring blog owners. Thankyou!

  331. Howdy, i read your blog occasionally and i own a similar one and i was just curious if you get a lot of spam responses? If so how do you stop it, any plugin or anything you can advise? I get so much lately it’s driving me insane so any support is very much appreciated.

  332. Wow that was odd. I just wrote an extremely long comment but after I clicked submit my comment didn’t show up. Grrrr… well I’m not writing all that over again. Anyways, just wanted to say fantastic blog!

  333. Hi, I think your site might be having browser compatibility issues. When I look at your blog site in Chrome, it looks fine but when opening in Internet Explorer, it has some overlapping. I just wanted to give you a quick heads up! Other then that, very good blog!

  334. Awesome blog! Is your theme custom made or did you download it from somewhere? A design like yours with a few simple tweeks would really make my blog stand out. Please let me know where you got your theme. Many thanks

  335. Hiya! I know this is kinda off topic however I’d figured I’d ask. Would you be interested in exchanging links or maybe guest writing a blog post or vice-versa? My site goes over a lot of the same topics as yours and I believe we could greatly benefit from each other. If you are interested feel free to shoot me an email. I look forward to hearing from you! Great blog by the way!

  336. Howdy! I know this is kinda off topic but I was wondering which blog platform are you using for this website? I’m getting sick and tired of WordPress because I’ve had issues with hackers and I’m looking at options for another platform. I would be great if you could point me in the direction of a good platform.

  337. Greetings from California! I’m bored at work so I decided to browse your blog on my iphone during lunch break. I enjoy the information you present here and can’t wait to take a look when I get home. I’m shocked at how fast your blog loaded on my cell phone .. I’m not even using WIFI, just 3G .. Anyhow, wonderful blog!

  338. My programmer is trying to convince me to move to .net from PHP. I have always disliked the idea because of the expenses. But he’s tryiong none the less. I’ve been using Movable-type on various websites for about a year and am anxious about switching to another platform. I have heard fantastic things about blogengine.net. Is there a way I can transfer all my wordpress content into it? Any help would be really appreciated!

  339. I am really enjoying the theme/design of your website. Do you ever run into any browser compatibility problems? A number of my blog readers have complained about my blog not working correctly in Explorer but looks great in Firefox. Do you have any solutions to help fix this issue?

  340. Please let me know if you’re looking for a author for your blog. You have some really good articles and I feel I would be a good asset. If you ever want to take some of the load off, I’d absolutely love to write some articles for your blog in exchange for a link back to mine. Please shoot me an email if interested. Many thanks!

  341. Appreciating the commitment you put into your blog and detailed information you provide. It’s good to come across a blog every once in a while that isn’t the same out of date rehashed information. Great read! I’ve saved your site and I’m including your RSS feeds to my Google account.

  342. Greetings from Los angeles! I’m bored at work so I decided to check out your site on my iphone during lunch break. I enjoy the information you provide here and can’t wait to take a look when I get home. I’m shocked at how quick your blog loaded on my cell phone .. I’m not even using WIFI, just 3G .. Anyways, wonderful site!

  343. Heya! I know this is sort of off-topic however I had to ask. Does building a well-established blog like yours take a massive amount work? I am brand new to blogging but I do write in my journal on a daily basis. I’d like to start a blog so I can easily share my personal experience and thoughts online. Please let me know if you have any suggestions or tips for new aspiring blog owners. Thankyou!

  344. Does your blog have a contact page? I’m having a tough time locating it but, I’d like to shoot you an email. I’ve got some ideas for your blog you might be interested in hearing. Either way, great blog and I look forward to seeing it develop over time.

  345. I’m really enjoying the theme/design of your site. Do you ever run into any browser compatibility problems? A small number of my blog readers have complained about my blog not working correctly in Explorer but looks great in Opera. Do you have any tips to help fix this issue?

  346. Do you mind if I quote a few of your articles as long as I provide credit and sources back to your webpage? My blog site is in the very same niche as yours and my visitors would certainly benefit from some of the information you present here. Please let me know if this alright with you. Thank you!

  347. I’m not sure why but this website is loading extremely slow for me. Is anyone else having this problem or is it a problem on my end? I’ll check back later and see if the problem still exists.

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